Pensito Flu Update: Seasonal Vaccine No Protection in Japan

From ProMed:

As of Friday, 29 May 2009, a total of 367 confirmed cases of human infection with a novel influenza A (H1N1) virus had been reported to Japanese Ministry of Health, Labor and Welfare (MHLW). Preliminary outbreak investigation report from National Institute of Infectious Diseases, Tokyo, Japan has provided important data on the effectiveness of pre-seasonal vaccination on the new strain.

They investigated 43 confirmed cases reported from Kobe City. Their median age was 17 years, which ranged from 5 to 44 years. Among them, 42 reported having had pre-seasonal vaccination for 2008-09 season and the coverage was 52.4 percent. According to MHLW’s estimates, the coverage of influenza vaccine among Japanese population was 53.7 percent for those aged less than 13 years, 23.1 percent for those 13 to 64 years, and 58.8 percent for those over 64 years during the 2008-09 season. Taking account of the population age structure, 27.9 percent of Japanese people ages 5 to 44 years are estimated to have been vaccinated for seasonal influenza virus. That indicates that vaccine coverage among confirmed cases is no less than that of the population average.

It is too early to reach a conclusion about a possible negative effect, yet it is already obvious that pre-seasonal vaccine for 2008-09 season has no
protective effect on disease from the novel influenza A (H1N1) strain among the Japanese population. This finding should be valuable information for
public health policy makers preparing for coming winter season.

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